In Vivo Systems Part A
Edited by David A. Cheresh
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Angiogenesis by David A. Cheresh
Book DescriptionAngiogenesis is the growth of new blood vessels and is an important natural process in the body. A healthy body maintains a perfect balance of angiogenesis modulators. In many serious disease states, however, the body loses control over angiogenesis. Diseases that are angiogenesis-dependent result when blood vessels either grow excessively or insufficiently. Understanding how angiogenesis 'works' and how to control it, will have massive implications on the management, treatments, and ultimately the prevention of many common (and not so common) diseases. Angiogenesis cuts across virtually every discipline. The Angiogenesis Foundation identified angiogenesis as a 'common denominator' in our most serious diseases. Excessive angiogenesis occurs in diseases such as cancer, diabetic blindness, age-related macular degeneration, rheumatoid arthritis, psoriasis, and many other conditions. Insufficient angiogenesis occurs in diseases such as coronary artery disease, stroke, and delayed wound healing. This book provides tried-and-tested techniques written by researchers that developed them, used them, and brought them to fruition. It provides the 'builder's manual' for essential techniques. This is a one-stop shop that eliminates needless searching among untested techniques. It includes step-by-step methods for understanding the cell and molecular basis of wound healing, vascular integrin signaling, mechanical signaling in blood vessels, and vascular proteomics.
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Book DetailsISBN: 9780123743138
(229mm x 152mm x 25mm)
Imprint: Academic Press Inc
Publisher: Elsevier Science Publishing Co Inc
Publish Date: 10-Nov-2008
Country of Publication: United States
Books By Author David A. Cheresh
Angiogenesis, Hardback (December 2008)
Angiogenesis is the growth of new blood vessels and is an important natural process in the body. This book includes step-by-step methods for understanding the cell and molecular basis of wound healing, vascular integrin signaling, mechanical signaling in blood vessels, and vascular proteomics.
Angiogenesis: In Vitro Systems, Hardback (October 2008)
Includes methods for understanding the cell and molecular basis of wound healing, vascular integrin signaling, mechanical signaling in blood vessels, and vascular proteomics.
Integrins, Hardback (October 2007)» View all books by David A. Cheresh
An integrin, or integrin receptor, is an integral membrane protein in the plasma membrane of cells. It plays a role in the attachment of a cell to the extracellular matrix (ECM) and to other cells, and in signal transduction from the ECM to the cell. This volume in "Methods in Enzymology" presents methods for studying integrins.
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