By (author) William Berger
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Asthma by William Berger
Book DescriptionAsthma is a common chronic inflammatory condition affecting the airways and displays a varied phenotypic picture. It is becoming increasingly recognized by healthcare workers and epidemiological studies suggest that along with other atopic diseases, its prevalence is rising. The precise etiology of asthma remains uncertain, but genetic and environmental factors such as viruses, country of origin, allergen exposure, early use of antibiotics, and numbers of siblings have all been implicated in its inception and development. Pathologically it is characterized by inflammation, physiologically by airway hyper-responsiveness (or hyper-reactivity) resulting in reversible airflow obstruction, and clinically by wheeze, chest tightness, breathlessness and cough. It can present in early childhood as well as adulthood, and varies markedly in severity, clinical course, subsequent disability and response to treatment. Exacerbations and symptoms of asthma are the final manifestation of a complex interplay between an array of inflammatory cells and mediators, which cause airway smooth muscle to intermittently relax and contract. Despite greater knowledge surrounding the immunopathological origins of asthma and considerable advances in its management, it remains one of the most important chronic diseases in young adults and poses a significant degree of morbidity throughout all age groups. A minority of patients experience difficulty in controlling asthma and pose significant therapeutic difficulties in specialist clinics. Exacerbations of asthma contribute to significant costs for healthcare systems and are implicated in adversely affecting the quality of life of individuals and their families. Moreover, although asthma deaths have decreased over the past few decades, an appreciable number of deaths still occur each year. Regular anti-inflammatory therapy with inhaled corticosteroids is required in all but the mildest of disease and attenuates underlying airway inflammation and hyper-responsiveness, while bronchodilators are designed to relax airway smooth muscle and prevent bronchoconstriction on exposure to bronchoconstrictor stimuli. Other forms of treatment are required in individuals with persistent symptoms and exacerbations. In recent years several potentially exciting treatments have emerged and are in varying degrees of development. Part of the new Oxford American Respiratory Library, this concise, portable guide provides an essential reference on current, evidence-based medical approaches to diagnosing and managing asthma. This practical volume features chapters on the pathophysiology of the disease with information on the common symptoms and potential triggers. In addition, the text includes discussions of new and emerging pharmacotherapies and complementary treatment therapies, with guidelines for symptom prevention.
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Book DetailsISBN: 9780195384390
(203mm x 129mm x 6mm)
Imprint: Oxford University Press Inc
Publisher: Oxford University Press Inc
Publish Date: 10-Apr-2009
Country of Publication: United States
Books By Author William Berger
Verdi with a Vengeance, Paperback (November 2001)
Provides background on the artist's childhood and struggle with success, scene-by-scene analyses of such operas as Aida, La traviata, and Don Carlos, and a discussion on his musical recordings.
Wagner without Fear, Paperback (June 2001)» View all books by William Berger
Provides background information on the artist, scene-by-scene analyses of his most famous operas, a critical discussion of musical recordings, and a crash course in opera "lobby talk".
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Author Biography - William Berger
Medicine, Department of Pediatrics, Division of Allergy and Immunology, and Adjunct Professor of Health Care Management in the Graduate School of Management at the University of California, Irvine. Dr. Berger has served as President of both, the Orange County and the California Societies of Allergy, Asthma, and Immunology. He is a member of the joint Task Force on Practice Parameters, Chairman of the Managed Care Committee of the American College of Allergy, Asthma and Immunology, and Chairman of the Mission Hospital Institutional Review board. A former Medical Correspondent for the Orange County News Channel, Dr. Berger is the author of many academic papers and lay press articles in the field of Allergy, Asthma, and Immunology, including the recently published book All ergies and Asthma for Dummies.
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