Cell Adhesion by Mary C. Beckerle
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Cell Adhesion
By Mary C. Beckerle

Cell Adhesion

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Format: Hardback

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Cell Adhesion by Mary C. Beckerle

Book Description

Cell adhesion plays a central role in development and disease. Cell adhesion to particular ligands can affect cytoskeletal organization and cell polarity, cell proliferation, and gene expression. This book is divided into two parts. The first section provides a discussion of the structure and function of the seven major classes of cell adhesion molecules: integrins, cadherins, selectins, heparan sulfate proteoglycans, the immunoglobulin superfamily, the ADAMs proteins, and transmembrane protein tyrosine phosphatases. The roles of these cell adhesion proteins in important processes such as cell mediated immunity, development and disease are discussed. In the second section, the molecular organization and function of junctional complexes, regions of the cell surface that are highly specialized for cell adhesion, are examined. Junctional complexes are now known to mediate adhesive interactions and contribute to transmembrane signaling events that dramatically influence cell behaviour. The biochemical organization of the adhesive membranes and the molecular mechanisms by which they transmit information to the cell are addressed. Written by contributors among the most prominent in the field, Cell Adhesion covers a wide range of topics in a single volume. It will be a great resource for students, teachers and researchers.

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Book Details

ISBN: 9780199638727
ISBN-10: 0199638721
Format: Hardback
(255mm x 195mm x 28mm)
Pages: 426
Imprint: Oxford University Press
Publisher: Oxford University Press
Publish Date: 21-Feb-2002
Country of Publication: United Kingdom

Other Editions...

Books By Author Mary C. Beckerle

Cell Adhesion by Mary C. Beckerle Cell Adhesion, Paperback (February 2002)

Cell adhesion, where a cell sticks to another cell or to the network of fibres surrounding cells, is critical for normal development and physiology. The book provides a series of current, in-depth, well-illustrated reviews, and covers the structures and functions of the major classes of cell adhesion molecules in a single volume.

» View all books by Mary C. Beckerle


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