Cytokine Network by Frances R. Balkwill
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Cytokine Network
By Frances R. Balkwill

The Cytokine Network

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Format: Paperback

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Cytokine Network by Frances R. Balkwill

Book Description

Cytokines are soluble mediators of intercellular communication. They contribute to a chemical signalling language that regulates development, tissue repair, haemopoiesis, inflammation and the immune response. Potent cytokine polypepides have pleiotropic activities and functional redundancy. They act in a complex network where one cytokine can influence the production of, and response to, many other cytokines. In the past five years, this bewildering array of more than 100 effector molecules and associated cell surface receptors has been simplified by study of cytokine and cytokine receptor structure; elucidation of convergent intracellular signalling pathways; and molecular genetics, and targeted gene disruption to 'knock-out' production of individual cytokines in mice. It is also now clear that the pathophysiology of infectious, autoimmune and malignant disease can be partially explained by the induction of cytokines and the subsequent cellular response. Viral homologues exist for many cytokines and receptors and genetic variations in cytokine production may influence response to pathogenic stimuli. Cytokine and cytokine antagonists have shown therapeutic potential in a number of chronic and acute diseases. The Cytokine Network: Frontiers in Molecular Biology is not a survey of individual cytokines, but guides the reader through the latest research on the cytokine network as a whole covering genomics, signalling pathways, control of the immune response, and therapeutics.

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Book Details

ISBN: 9780199637027
ISBN-10: 0199637024
Format: Paperback
(245mm x 188mm x 13mm)
Pages: 216
Imprint: Oxford University Press
Publisher: Oxford University Press
Publish Date: 10-Feb-2000
Country of Publication: United Kingdom

Other Editions...


Books By Author Frances R. Balkwill

Cytokine Molecular Biology by Frances R. Balkwill Cytokine Molecular Biology, Paperback (November 2000)

The study of cytokines is central to biomedical research as they are involved in regulating development, tissue repair, haemopoiesis, inflammation, and the immune response. The field has grown so much in the past 5 years that the third edition has expanded into two volumes, one concentrating on molecular biology and the other on cellular biology.

Cytokine Cell Biology by Frances R. Balkwill Cytokine Cell Biology, Paperback (November 2000)

The study of cytokines is central to biomedical research as they are involved in regulating development, tissue repair, haemopoiesis, inflammation, and the immune response. The field has grown so much in the past 5 years that the third edition has expanded into two volumes, one concentrating on molecular biology and the other on cellular biology.

Cytokines by Frances R. Balkwill Cytokines, Paperback (September 1995)

Cytokines are proteins that control communications between cells in the body and are important in immunity, inflammation, tissue development, tissue repair, and cancer. This book is a comprehensive guide to methods for studying cytokines and will be of wide use and interest.

» View all books by Frances R. Balkwill

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Recent books by Frances R. Balkwill close
Cytokine Molecular Biology by Frances R. Balkwill
Cytokine Cell Biology by Frances R. Balkwill
Cytokines by Frances R. Balkwill
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