Fragment-based Drug Discovery by Edward Zartler
Look inside with Google Book Preview
Fragment-based Drug Discovery
By Edward Zartler

Fragment-based Drug Discovery

A Practical Approach

Edited by See other recent books by Edward Zartler See other recent books by Michael Shapiro
Format: Hardback

Normal Price: $340.95
Your Price: $306.86 AUD, inc. GST
Shipping: $6.95 per order
You Save: $34.09! (10% off normal price)
Plus...earn $15.34 in Boomerang Bucks
Availability: Available Available to Backorder, No Due Date for Supply



Fragment-based Drug Discovery by Edward Zartler

Book Description

Fragment-based drug discovery (FBDD) is a new paradigm in drug discovery that utilizes very small molecules - fragments of larger molecules. It is a faster, cheaper, smarter way to do drug discovery, as shown by the number of pharmaceutical companies that have embraced this approach and the biotechnology companies who use fragments as their sole source of drug discovery. Fragment-Based Drug Discovery: A Practical Approach is a guide to the techniques and practice of using fragments in drug screening. The emphasis is on practical guidance, with procedures, case studies, practical tips, and contributions from industry. Topics covered include: an introduction to fragment based drug discovery, why using fragments is a more efficient process than predominant models, and what it means to have a successful FBDD effort. setting up an FBDD project library building and production NMR in fragment screening and follow up application of protein-ligand NOE matching to the rapid evaluation of fragment binding poses target immobilized NMR screening: validation and extension to membrane proteins in situ fragment-based medicinal chemistry: screening by mass spectrometry computational approaches to fragment and substructure discovery and evaluation virtual fragment scanning: current trends, applications and web based tools fragment-based lead discovery using covalent capture methods case study from industry: the identification of high affinity beta-secretase inhibitors using fragment-based lead generation With contributions from industry experts who have successfully set up an industrial fragment-based research program, Fragment-Based Drug Discovery: A Practical Approach offers essential advice to anyone embarking on drug discovery using fragments and those looking for a new approach to screening for drugs.

Buy Fragment-based Drug Discovery book by Edward Zartler from Australia's Online Bookstore, Boomerang Books.


Book Details

ISBN: 9780470058138
ISBN-10: 0470058137
Format: Hardback
(247mm x 169mm x 21mm)
Pages: 296
Imprint: Wiley-Blackwell
Publisher: John Wiley and Sons Ltd
Publish Date: 17-Oct-2008
Country of Publication: United States

Reviews

» Have you read this book? We'd like to know what you think about it - write a review about Fragment-based Drug Discovery book by Edward Zartler and you'll earn 50c in Boomerang Bucks loyalty dollars (you must be a member - it's free to sign up!)

Write a book review


Boomerang Bucks close

For every $20 you spend on books, you will receive $1 in Boomerang Bucks loyalty dollars. You can use your Boomerang Bucks as a credit towards a future purchase from Boomerang Books. Note that you must be a Member (free to sign up) and that conditions do apply.

Recent books by Edward Zartler close
»
Recent books by Michael Shapiro close
Genre and the City by Michael Shapiro
Bottom of the Ninth by Michael Shapiro
Fragment-based Drug Discovery by Michael Shapiro
Challenging Euro-America's Politics of Identity by Michael Shapiro
Sense of Place by Michael Shapiro
Solomon's Sword by Michael Shapiro
»
BoomerangBooks.com.au close