GABA in Autism and Related Disorders
Volume editor Dirk Dhossche
GABA in Autism and Related Disorders by Dirk Dhossche
Book DescriptionGamma-aminobutyric acid (GABA) was discovered in the brain in 1950 by Eugene Roberts. GABA is now considered one of the most important neurotransmitters and developmental signals. Knowledge on the complexity of GABA function is increasing exponentially. This volume covers basic research on GABA in the developing brain as it may relate to onset of autism and related developmental disorders. The evidence that dysfunction of GABA and related molecules is associated with autism is limited but expanding and seems to converge. Pertinent data are reviewed in this book and new research avenues in the basic and clinical arenas are described. The topics are of imminent interest to basic and clinical researchers as well as interested clinicians. It: discusses the neuropathology of the GABA system in autism; presents new findings on common genetic mechanisms in Rett syndrome, Angelman syndrome, and autism; includes information on the shared genetic risk factors between autism and major mental disorders; and foreword by Eugene Roberts.
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Book DetailsISBN: 9780123668721
(229mm x 152mm x 27mm)
Imprint: Academic Press Inc
Publisher: Elsevier Science Publishing Co Inc
Publish Date: 20-Dec-2005
Country of Publication: United States
Books By Author Dirk Dhossche
Catatonia in Autism Spectrum Disorders, Hardback (March 2006)» View all books by Dirk Dhossche
The interest in the relation between autism and catatonia stems from clinical observations that autistic and catatonic symptoms overlap, that some people with autism develop catatonia, and that anti-catatonic treatments bring relief in some of those patients. This book explores the question of if the two syndromes have a common pathophysiology.
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