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Galectins by Anatole A. Klyosov
Book DescriptionThe comprehensive guide to the current understanding of galectins and their promising potential in drug design This is the first book focusing on galectins. It was inspired by topics discussed at the symposium "Galectins: Structures, Functions, and Therapeutic Targets" that was a part of the 234th American Chemical Society meeting in 2007. To help chemists, biochemists, and others understand the challenges inherent in the study of galectins and build on recent advances in the field, the editors have compiled articles from leading experts on galectins and their biomedical applications. Galectins includes: An overview of early galectin research An explanation of the nature of galectins A discussion of the structure and functions of galectins, their ligand specificity and molecular mechanisms of action, and the localization of galectins in the cell An exploration of the roles galectins play in tumor growth and cancer, fibrosis, inflammation, and immunity A discussion of the effect of galectins on cell migration, angiogenesis, and chemoresistance An introduction to new approaches to designing galectin inhibitors This is the premier reference on galectins for organic, medicinal, carbohydrate, and pharmaceutical chemists, biochemists, molecular and cell biologists, pharmacologists, cancer researchers, and graduate-level students in these disciplines, as well as clinicians and drug developers.
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Book DetailsISBN: 9780470373187
(234mm x 163mm x 24mm)
Publisher: John Wiley and Sons Ltd
Publish Date: 1-Aug-2008
Country of Publication: United States
Books By Author Anatole A. Klyosov
Galectins and Disease Implications for Targeted Therapeutics, Hardback (July 2013)
Provides discussion of the latest work in Galectins, stemming from the Symposium 'Galectin Functions and Therapeutics.'
Wood-plastic Composites, Hardback (September 2007)» View all books by Anatole A. Klyosov
A comprehensive, practical guide to wood-plastic composites and their properties This is the first book that presents an overview of the main principles underlying the composition of wood-plastic composite (WPC) materials and their performance in the real world.
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Author Biography - Anatole A. Klyosov
Anatole A. Klyosov, PhD, is Chief Scientist and cofounder of Pro-Pharma-ceuticals, Inc. He has published more than 290 peer-reviewed articles in scientific journals; authored and edited books on enzymes, carbohydrates, and biotechnology, including Wood-Plastic Composites (Wiley); and holds thirty-nine patents. Zbigniew J. Witczak, PhD, has extensive industrial and academic experience in carbohydrates. He has published more than ninety research papers and holds six patents in the fields of carbohydrate, medicinal, and biological chemistry. In 2000, Dr. Witczak was awarded the Melville L. Wolfrom Award of the ACS Division of Carbohydrate Chemistry for his outstanding research contribution to carbohydrate chemistry and service to the division. David Platt, PhD, is Chief Executive Officer and cofounder of Pro-Pharmaceuticals, Inc. He has published peer-reviewed articles and holds many patents, primarily in the field of carbohydrate chemistry. Dr. Klyosov, Dr. Witczak, and Dr. Platt coedited the ACS symposium book Carbohydrate Drug Design.
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