Genomic Signal Processing
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Genomic Signal Processing by Ilya Shmulevich
Book DescriptionGenomic signal processing (GSP) can be defined as the analysis, processing, and use of genomic signals to gain biological knowledge, and the translation of that knowledge into systems-based applications that can be used to diagnose and treat genetic diseases. Situated at the crossroads of engineering, biology, mathematics, statistics, and computer science, GSP requires the development of both nonlinear dynamical models that adequately represent genomic regulation, and diagnostic and therapeutic tools based on these models. This book facilitates these developments by providing rigorous mathematical definitions and propositions for the main elements of GSP and by paying attention to the validity of models relative to the data. Ilya Shmulevich and Edward Dougherty cover real-world situations and explain their mathematical modeling in relation to systems biology and systems medicine. Genomic Signal Processing makes a major contribution to computational biology, systems biology, and translational genomics by providing a self-contained explanation of the fundamental mathematical issues facing researchers in four areas: classification, clustering, network modeling, and network intervention.
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Book DetailsISBN: 9780691117621
(229mm x 152mm x 19mm)
Imprint: Princeton University Press
Publisher: Princeton University Press
Publish Date: 2-Jul-2007
Country of Publication: United States
Books By Author Ilya Shmulevich
Probabilistic Boolean Networks, Paperback (January 2010)
The first comprehensive treatment of probabilistic Boolean networks, unifying different strands of current research and addressing emerging issues.
Microarray Quality Control, Hardback (March 2004)» View all books by Ilya Shmulevich
Microarray technology provides researchers in the life sciences with a revolutionary tool for measuring gene expression. However, this highly developed process involves multiple steps, from sample selection to data analysis, each susceptible to potentially costly errors.
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Author Biography - Ilya Shmulevich
Ilya Shmulevich, an associate professor at the Institute for Systems Biology, is the coauthor of "Microarray Quality Control" and the coeditor of "Computational and Statistical Approaches to Genomics". Edward R. Dougherty is professor of electrical and computer engineering and director of the Genomic Signal Processing Laboratory at Texas A&M University, and director of the Computational Biology Division at the Translational Genomics Research Institute. His thirteen previous books include "Random Processes for Image and Signal Processing".
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