Glutathione Transferases and Gamma-Glutamyl Transpeptidases
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Glutathione Transferases and Gamma-Glutamyl Transpeptidases by Helmut Sies
Book DescriptionThis volume on glutathione transferases and gamma-glutamyl transpeptidases serves to bring together current methods and concepts in an interesting, important and rapidly developing field of cell and systems biology. It focuses on particular aspects of the so-called Phase II of drug detoxication, which has important ramifications for endogenous metabolism and nutrition. This volume of "Methods in Enzymology" presents current knowledge and in this field of research. Together with the volumes on "Quinones" and "Quinone Enzymes" (volumes 378 and 382), and on Phase II "Conjugation Enzymes and Transport Systems" (volume 400), the state of knowledge on proteomics and metabolomics of many pathways of (waste) product elimination, enzyme protein induction and gene regulation and feedback control is provided. We trust that this volume will help stimulate future investigations and speed the advance of knowledge in systems biology. It is a laboratory standard for more than 40 years. It is over 400 volumes strong. It is also available on ScienceDirect.
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Book DetailsISBN: 9780121828066
(229mm x 152mm x 27mm)
Imprint: Academic Press Inc
Publisher: Elsevier Science Publishing Co Inc
Publish Date: 12-Dec-2005
Country of Publication: United States
Books By Author Helmut Sies
Oxygen Biology and Hypoxia, Hardback (November 2007)
Part of the "Methods in Enzymology" series, which is a publication in the field of biochemistry, this volume features articles on the topic of oxygen biology and hypoxia. It is suitable for researchers in the fields of life and related sciences.
Osmosensing and Osmosignaling, Hardback (November 2007)
Features articles on the topic of osmosensing and osmosignaling written by experts in the field.
Phase II Conjugation Enzymes and Transport Systems, Hardback (December 2005)» View all books by Helmut Sies
Focuses on the Phase II enzymes of drug metabolism (xenobiotics), which has important ramifications for endogenous metabolism and nutrition. This volume presents the knowledge and methodology on glucuronidation, sulfation, acetylation, and transport systems in this field of research. It also includes aspects on Phase III, transport systems.
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Author Biography - Helmut Sies
Helmut Sies is an Honorary Member of the American Society for Biochemistry and Molecular Biology. He received an Honorary Ph.D. from the University of Buenos Aires, Argentina in 1996. Dr. Sies is a member of the Northrhine-Westphalian Academy of Sciences, Germany, and a Corresponding Member of both the Academy of Sciences of Heidelberg, Germany, and the Academy of Medicine, Buenos Aires, Argentina. He has received many awards and prizes, including the FEBS Anniversary Prize awarded by the Federation of European Biochemical Societies, 1978; the Distinguished Foreign Scholar award, MASUA, 1985; the Silver Medal, Karolinska Institute, Stockholm, 1986; the Ernst Jung Preis fur Medizin, 1988; the Claudius-Galenus-Preis, 1990; and the ISFE-Preis, 1994. Dr. Sies sereves on the editorial board and advisory committee for twelve journals, has edited numerous books, and has published more than 400 original articles and chapters. He received his M.D. at the University of Munich in 1967 and currently serves as Full Professor and Chairman of the Department of Physiological Chemistry at the University of Dusseldorf.
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