Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas
Molecular Pathology, Colorectal Carcinoma, and Prostate Carcinoma
Edited by M. A. Hayat
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Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas by M. A. Hayat
Book DescriptionImmunohistochemistry is the use of specific antibodies to stain particular molecular species in situ. This technique has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system, and has the potential to improve diagnosis, prognosis and therapeutic options of cancer. This book discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. The topics of region-specific gene expression, its role in cancer development and the techniques that assist in the understanding of the molecular basis of disease are relevant and necessary in science today. This book is the second volume of three planned, individually-sold volumes on this topic. Like Volume 1, this book fully explains the principles and applications of modern techniques used in the field of molecular genetics. It will be of particular interest to pathologists and molecular pathologists conducting both academic and/or clinical research. It is the only book available that translates molecular genetics into cancer diagnosis. The results of each Immunohistochemical and in situ hybridization method are presented in the form of color illustrations. The methods discussed were either developed or refined by expert contributors in their own laboratories.
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Book DetailsISBN: 9780123339423
(279mm x 216mm x 30mm)
Imprint: Academic Press Inc
Publisher: Elsevier Science Publishing Co Inc
Publish Date: 31-Jan-2005
Country of Publication: United States
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Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas, Hardback (June 2004)» View all books by M. A. Hayat
Discusses various aspects of immunohistochemistry and in situ hybridization technologies and the role they play in reaching a cancer diagnosis. This work provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, and the benefits and limitations of each method.
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Author Biography - M. A. Hayat
Dr. Hayat has published extensively in the fields of microscopy, cytology, immunohistochemistry, immunocytochemistry, and antigen retrieval methods. He is Distinguished Professor, Department of Biological Sciences, Kean University, Union, New Jersey, USA.
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