The Handbook of Metabonomics and Metabolomics
Normal Price: $307.00
Your Price: $276.30 AUD, inc. GST
Shipping: $7.95 per order
You Save: $30.70! (10% off normal price)
Plus...earn $13.82 in Boomerang Bucks
Availability: Available to Backorder, No Due Date for Supply
Handbook of Metabonomics and Metabolomics by John C. Lindon
Book DescriptionMolecular biology operates at three levels: genes, proteins and metabolites. This book is unique in that it provides a comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies (genomics and proteomics). These "omics" methods form the basis for understanding biology at a systems level. "The Handbook of Metabonomics and Metabolomics" aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification, encompassing the fields of metabonomics and metabolomics. It covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications. It offers a comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies; aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification; and, covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications.
Buy Handbook of Metabonomics and Metabolomics book by John C. Lindon from Australia's Online Bookstore, Boomerang Books.
Book DetailsISBN: 9780444528414
(240mm x 165mm x 26mm)
Imprint: Elsevier Science Ltd
Publisher: Elsevier Science & Technology
Publish Date: 11-Dec-2006
Country of Publication: United Kingdom
Books By Author John C. Lindon
NMR in Pharmaceutical Science, Hardback (September 2015)» View all books by John C. Lindon
NMR in Pharmaceutical Sciences is intended to be a comprehensive source of information for the many individuals that utilize MR in studies of relevance to the pharmaceutical sector.
» Have you read this book? We'd like to know what you think about it - write a review about Handbook of Metabonomics and Metabolomics book by John C. Lindon and you'll earn 50c in Boomerang Bucks loyalty dollars (you must be a member - it's free to sign up!)
Author Biography - John C. Lindon
John Lindon is a Professor and Senior Research Investigator in the Division of Computational and Systems Medicine, part of the Department of Surgery and Cancer, Imperial College London, UK. He is also a founder Director of, and a Consultant to, Metabometrix Ltd, a company spun out of Imperial College to exploit the commercial possibilities of metabolic phenotyping. He obtained his B.Sc (1966), Ph.D. (1969) and D.Sc (1993) degrees from Birmingham University UK. He was a postdoctoral fellow at Columbia University, New York, USA (1969-1970), and then joined the Chemistry Department of Southampton University UK, to use NMR methods to research the properties of liquid crystals and later as a faculty member. From 1976 to 1995 he was at the Wellcome Research Laboratories (a pharmaceutical company) in the UK, occupying several senior scientific and managerial roles related to the use of physical chemical methods in drug design and discovery, latterly as Head of Spectroscopy, until they were taken over by Glaxo, now part of GlaxoSmithKline, in 1995. He then joined Birkbeck College, University of London and moved to Imperial College London as part of the transfer of the Jeremy Nicholson team in 1998. He has co-authored a book on NMR of oriented molecules, another on metabonomics in toxicology, one on metabonomics in general, one on NMR in pharmaceutical R&D and one on metabolic phenotyping in personalised medicine and population screening. He is Editor-in-Chief of the Encyclopedia of Spectroscopy and Spectrometry, is on the editorial board of a number of journals and has authored many review articles and chapters, plus more than 450 research papers. He has given many keynote, plenary and invited lectures around the world. His major research interest is the use of NMR and other analytical methods coupled with multivariate statistics to study biofluids and tissues, a field now termed metabolic phenotyping, leading to new approaches for disease diagnosis, prediction of outcomes and assessing disease risks in populations. His other achievements include the pioneering of a range of NMR data acquisition and processing methods, the use of nematic liquid crystals and NMR spectroscopy for determining accurate molecular structures in the liquid state, and the application of spectroscopy and other physical chemistry methods in drug design. Developments of NMR-based approaches in biomedical research include the use of directly-coupled HPLC-NMR for mixture analysis and application of high resolution magic-angle-spinning NMR to tissue samples. Nicholson obtained his BS in molecular toxicology and inorganic biochemistry from Liverpool University in 1977 and his PhD from London University in 1980. He has worked at Birkbeck College, London University, at the London School of Pharmacy and at Imperial College London and has held honorary professorships at six universities and two professorships at the Chinese Academy of Sciences, of which he was elected as an Albert Einstein Honorary Professor in 2014. He is also founder director, chief scientist and chief scientist officer at Metabometrix, an Imperial College spin-off company specializing in molecular phenotyping, clinical diagnostics and toxicological screening via metabonomics and metabolomics. His research interests include spectroscopic and chemometric approaches to the investigation of disturbed metabolic processes in complex organisms. Nicholson has received numerous grants and awards for his work, recent awards including the Theophilus Redwood Award of the Royal Society of Chemistry (2008) and the Interdisciplinary Award of the Royal Society of Chemistry for "his contributions to chemical biology, particularly mechanistic insights into disease and toxicity through the development of the field of metabonomics" (2007). Prof. Holmes is the Head of the Division of Computational and Systems Medicine and a Professor of Chemical Biology in the Department of Surgery and Cancer at Imperial College in London. She has over 20 years' experience in metabonomic technology and its applications. Her focus is on the discovery and development of metabolic biomarkers of disease in personalised healthcare and population studies with significant contributions to cardiovascular, neuroscience and infectious disease research. Recently Prof. Holmes has driven large-scale profiling efforts defining the concept of the metabolome-wide association study (MWAS) in molecular epidemiology, specifically exploring the link between hypertension, diet and metabolic profiles. She has also developed methods for characterizing gut microbiome host metabolic interactions and has applied these to the study of gastrointestinal related diseases including colorectal cancer, obesity and IBD. She also has an established track record in the development of chemometric and statistical methods for analysis of Omics data.
Bestselling Books: Our Current Bestsellers | Australia's Hottest 1000 Books | Bestselling Fiction | Bestselling Crime Mysteries and Thrillers | Bestselling Non Fiction Books | Bestselling Sport Books | Bestselling Gardening and Handicrafts Books | Bestselling Biographies | Bestselling Food and Drink | Bestselling History | Bestselling Travel Books | Bestselling School Textbooks & Study Guides | Bestselling Children's General Non-Fiction | Bestselling Young Adult Fiction | Bestselling Children's Fiction | Bestselling Picture Books | Top 100 US Bestsellers
Phone: 1300 36 33 32 (9am-5pm Mon-Fri AEST) - International: +61 2 9960 7998 - Online Form
Address: Boomerang Books, 878 Military Road, Mosman Junction, NSW, 2088
© 2003-2016. All Rights Reserved. Eclipse Commerce Pty Ltd - ACN: 122 110 687 - ABN: 49 122 110 687
For every $20 you spend on books, you will receive $1 in Boomerang Bucks loyalty dollars. You can use your Boomerang Bucks as a credit towards a future purchase from Boomerang Books. Note that you must be a Member (free to sign up) and that conditions do apply.