The Genetic and Cellular Logic of Pattern Formation
By (author) Lewis I. Held, Jr.
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Imaginal Discs by Lewis I. Held, Jr.
Book DescriptionMany of the 14,000 genes of Drosophila are involved in the development of imaginal discs. These hollow sacs of cells make adult structures during metamorphosis, and their study is crucial to comprehending how a larva becomes a fully-functioning fly. This book examines the genetic circuitry of the well-known 'fruit fly', tackling questions of cell assemblage and pattern formation, of the hows and the whys behind the development of the fly. After an initial examination of the proximity versus pedigree imperatives, the book delves into bristle pattern formation and disc development, with entire chapters devoted to the leg, wing, and eye. Extensive appendices include a glossary of protein domains, catalogues of well-studied genes, and an outline of signaling pathways. More than 30 wiring diagrams among over 60 detailed schematics clarify the text. No student or practising scientist engaged in the study of Drosophila genetics should be without this comprehensive reference.
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Book DetailsISBN: 9780521584456
(279mm x 215mm x 30mm)
Imprint: Cambridge University Press
Publisher: Cambridge University Press
Publish Date: 13-May-2002
Country of Publication: United Kingdom
Books By Author Lewis I. Held, Jr.
Deep Homology?, Paperback (February 2017)
A comparison of the genetic circuits of Homo sapiens and Drosophila reveals the evidence for deep homology.
How the Snake Lost its Legs, Paperback (January 2014)
This book explores the latest developments in evo-devo to explain the science behind tiger stripes, camel humps, and other fascinating animal traits.
Quirks of Human Anatomy, Hardback (May 2009)
This book introduces students to basic concepts in evolutionary developmental biology, for undergraduate and graduate courses.
Imaginal Discs, Paperback (August 2005)» View all books by Lewis I. Held, Jr.
Examines the genetic circuitry of the 'fruit fly', tackling the hows and the whys behind fly development.
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