Kinetic Analysis of Macromolecules
A Practical Approach
Edited by Kenneth Johnson
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Kinetic Analysis of Macromolecules by Kenneth Johnson
Book DescriptionModern enzymology can no longer rely upon indirect inferences derived by steady state kinetic analysis because these are often misleading. Rather, in the era of "New Enzymology", reactions at the active sites of enzyme are monitored by direct measurement of individual steps in the sequence to establish the pathway of reactions occurring. These quantitative methods can be directly related to high resolution structural information and define the underlying kinetic and thermodynamic basis for catalysis. The goal of a comprehensive kinetic analysis is to identify each step in the reaction pathway, define the rate and equilibrium constants for each step, identify all conformational and chemical intermediates, identify the rate-limiting steps, and ultimately establish the basis for enzymatic specificity and efficiency. This volume contains chapters contributed by leading experts in the application of modern kinetic methods to complex problems in the study of catalysis by both proteins and RNA catalysts.
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Book DetailsISBN: 9780198524946
(246mm x 190mm x 15mm)
Imprint: Oxford University Press
Publisher: Oxford University Press
Publish Date: 18-Sep-2003
Country of Publication: United Kingdom
Books By Author Kenneth Johnson
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Authoritative reviews and focused case studies on the history and future of the fauna and flora of Southeast Asia.
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Tells the story of mysterious Alien visitors who are ready to solve Earth's problems. This title tells how soon after arriving, the Aliens' true nature is revealed, but, as with so many oppressive regimes of Earth's past, as long as people are not directly under attack, they will turn a blind eye to their tyrannical overlords.
Fundamentals of Vedic Astrology, Paperback (March 2004)» View all books by Kenneth Johnson
This book introduces the concepts and operations of Vedic Astrology. It presents the component's of the astrologer's art-the planets, signs, houses and lunar mansions. The author goes into the rules that determine planetary strength, the construction of the divisional charts and the principal combinations, and much more.
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Author Biography - Kenneth Johnson
Kenneth A. Johnson Roger Williams Centennial Professor of Biochemistry Institute for Cell & Molecular Biology, University of Texas, A4800 MBB 3.122, Austin, TX 78735 512-471-0434 512-471-0435 firstname.lastname@example.org Roger Williams Centennial Professor of Biochemistry The University of Texas at Austin Recipient of Pfizer Award in Enzyme Chemistry, 1989 Founder and President of KinTek Corporation, manufacturer of stopped-flow and quench-flow instruments for fast reaction kinetics. Editorial Board Member, Journal of Biological Chemistry
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