Microarray Technology in Practice
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Microarray Technology in Practice by Steve Russell
Book DescriptionUsing chips composed of thousands of spots, each with the capability of holding DNA molecules corresponding to a given gene, DNA microarray technology has enabled researchers to measure simultaneously gene expression across the genome. As with other large-scale genomics approaches, microarray technologies are broadly applicable across disciplines of life and biomedical sciences, but remain daunting to many researchers. This guide is designed to demystify the technology and inform more biologists about this critically important experimental technique. * Cohesive overview of the technology and available platforms, followed by detailed discussion of experimental design and analysis of microarray experiments * Up-to-date description of normalization methods and current methods for sample amplification and labeling * Deep focus on oligonucleotide design, printing, labeling and hybridization, data acquisition, normalization, and meta-analysis * Additional uses of microarray technology such as ChIP (chromatin immunoprecipitation) with hybridization to DNA arrays, microarray-based comparative genomic hybridization (CGH), and cell and tissue arrays
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Book DetailsISBN: 9780123725165
(229mm x 152mm x 25mm)
Imprint: Academic Press Inc
Publisher: Elsevier Science Publishing Co Inc
Publish Date: 18-Nov-2008
Country of Publication: United States
Books By Author Steve Russell
Conjunction, Paperback (March 2016)
100 photographs of sculpture, paintings, and sketches place Clarke's and Chadwick's arresting forms side by side, showing the convergences and divergences of their kindred sculptural instincts. And both an essay by Judith LeGrove and an introduction by Polly Bielecka describe Clarke and Chadwick's parallel careers and characters.
Hofner, Paperback (November 2013)
Violin Bass Guitar is one of the most instantly recognisable musical instruments ever made. Its fame was assured when a certain young English guitarist walked into a shop in Hamburg in 1961, saw exactly what he was looking for, and ordered a left-handed version. The rest, as they say, is history. This book charts the history of the Violin Bass.
Challenge of Health Sector Reform, Hardback (November 2000)» View all books by Steve Russell
Examines the feasibility and desirability of health sector reforms in low-income countries, asking whether governments are capable of these roles. The text challenges conventional wisdom, arguing that reform approaches must be sensitive to the institutional characteristics of individual countries.
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