Neuroinflammation in Neuronal Death and Repair
Normal Price: $238.95
Your Price: $215.06 AUD, inc. GST
Shipping: $7.95 per order
You Save: $23.89! (10% off normal price)
Plus...earn $10.75 in Boomerang Bucks
Availability: Available to Backorder, No Due Date for Supply
Neuroinflammation in Neuronal Death and Repair by Giacinto Bagetta
Book DescriptionNeuroinflammation has been implicated recently in the pathogenesis of many neurodegenerative diseases. The cross-talk between neurons and non-neuronal cells seems to be a critical step in the progression of neurodegeneration and molecules that have a beneficial role may turn into harmful players. Thus, matrix metalloproteinases (MMPs), which are involved in axonal growth and regeneration as well as synaptic plasticity, may also have detrimental effects. Recent evidence has linked MMPs to conditions like ischemia, multiple sclerosis, Alzheimer's disease and suggested that, together with their role in the degradation of extracellular macromolecules, MMPs could work as important signalling molecules from injured neurons to the microglia. Thus, MMP-3 has been shown to induce the release of pro-inflammatory cytokines from microglia via activation of ERK and NF-kB-dependent pathways. Increasing evidence highlights the importance of a balanced cross-talk between neurons and non-neuronal cells and indicates that the presence of reactive astrocytes, the activation of microglia and the release of inflammatory mediators may contribute to the progression of many central nervous system disorders, independently of the nature of the primary pathogenic event. However, many aspects still remain controversial and much more effort is needed to understand the role of neuroinflammatory mediators and processes in these conditions. This volume brings together renowned, international scientists to discuss current knowledge and views on the mechanisms of neuroinflammation, on its role in the context of different neurodegenerative diseases (i.e. Alzheimer's, prion disease, HIV-associated dementia, multiple sclerosis, pain) and on the potential approaches for future therapeutic strategies.
Buy Neuroinflammation in Neuronal Death and Repair book by Giacinto Bagetta from Australia's Online Bookstore, Boomerang Books.
Book DetailsISBN: 9780123739896
(229mm x 152mm x 27mm)
Imprint: Academic Press Inc
Publisher: Elsevier Science Publishing Co Inc
Publish Date: 16-Oct-2007
Country of Publication: United States
Books By Author Giacinto Bagetta
New Trends in Basic and Clinical Research of Glaucoma: A Neurodegenerative Disease of the Visual System, Hardback (October 2015)
Herbal Medicines, Hardback (September 2011)» View all books by Giacinto Bagetta
While discussion concerning the validity of the plant approach to nutrition and disease treatment continues, the explosion of natural product use has generated concern regarding their effectiveness and possible danger. Using a rational, sequential approach, this book explores the development of efficacious medicinal herbal products.
» Have you read this book? We'd like to know what you think about it - write a review about Neuroinflammation in Neuronal Death and Repair book by Giacinto Bagetta and you'll earn 50c in Boomerang Bucks loyalty dollars (you must be a member - it's free to sign up!)
Bestselling Books: Our Current Bestsellers | Australia's Hottest 1000 Books | Bestselling Fiction | Bestselling Crime Mysteries and Thrillers | Bestselling Non Fiction Books | Bestselling Sport Books | Bestselling Gardening and Handicrafts Books | Bestselling Biographies | Bestselling Food and Drink | Bestselling History | Bestselling Travel Books | Bestselling School Textbooks & Study Guides | Bestselling Children's General Non-Fiction | Bestselling Young Adult Fiction | Bestselling Children's Fiction | Bestselling Picture Books | Top 100 US Bestsellers
Phone: 1300 36 33 32 (9am-5pm Mon-Fri AEST) - International: +61 2 9960 7998 - Online Form
Address: Boomerang Books, 878 Military Road, Mosman Junction, NSW, 2088
© 2003-2017. All Rights Reserved. Eclipse Commerce Pty Ltd - ACN: 122 110 687 - ABN: 49 122 110 687
For every $20 you spend on books, you will receive $1 in Boomerang Bucks loyalty dollars. You can use your Boomerang Bucks as a credit towards a future purchase from Boomerang Books. Note that you must be a Member (free to sign up) and that conditions do apply.