The Organic Chemistry of Drug Synthesis
By (author) Daniel Lednicer
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Organic Chemistry of Drug Synthesis by Daniel Lednicer
Book DescriptionThe classic reference on the synthesis of medicinal agents --now completely updated The seventh volume in the definitive series that provides a quick yet thorough overview of the synthetic routes used to access specific classesof therapeutic agents, this volume covers approximately 220 new non-proprietary drug entities introduced since the publication of Volume 6.Many of these compounds represent novel structural types firstidentified by sophisticated new cell-based assays. Specifically, a significant number of new antineoplastic and antiviral agents are covered. As in the previous volumes, materials are organized by chemical class and syntheses originate with available starting materials. Organized to make the information accessible, this resource covers disease state, rationale for method of drug therapy, and the biological activities of each compound and preparation. The Organic Chemistry of Drug Synthesis, Volume 7 is a hands-on reference for medicinal and organic chemists, and a great resource for graduate and advanced undergraduate students in organic and medicinal chemistry.
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Book DetailsISBN: 9780470107508
(234mm x 162mm x 20mm)
Publisher: John Wiley and Sons Ltd
Publish Date: 20-Nov-2007
Country of Publication: United States
Books By Author Daniel Lednicer
Antineoplastic Drugs, Hardback (May 2015)
Deals with the organic chemistry involved in the synthesis of the agents found within antineoplastic drugs, including descriptions of the synthetic schemes for the preparation of over 200 compounds that have been granted non-proprietary names. This volume also focuses on the syntheses of established chemotherapy drugs.
Steroid Chemistry at a Glance, Hardback (October 2010)
Androgen steroids have become virtually synonymous with drug abuse in sports but are in reality overshadowed by a large collection of compounds, which are commercial drugs that share the same structural carbon skeleton. Steroid Chemistry At A Glance provides a concise overview of the main principles and reactions of steroid chemistry.
Strategies for Organic Drug Synthesis and Design, Hardback (November 2008)
This book examines and evaluates the strategies utilized to design and synthesize pharmaceutically active agents. Significant updates over the last 10 years since the publication of the 1st edition include synthesis of enantiomerically pure isomers, novel chemical methodologies, and new pharmaceutical agents targeted at novel biological endpoints.
New Drug Discovery and Development, Hardback (November 2006)» View all books by Daniel Lednicer
A case history approach to drug synthesis and discovery Discover the origins of some of today's most popular drug therapies. Explore case histories and gain insight into major classes of antibiotics, antiviral drugs, analgesics, steroids, compounds designed to lower cholesterol, and more.
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Author Biography - Daniel Lednicer
Daniel Lednicer, PhD, is the author of several books on drug synthesis and discovery. His career in both the private and public sectors has been devoted to the search for new therapeutic agents. Dr. Lednicer spent two decades at the bench as a chemist at the Upjohn Company. Following that, he served as director of chemical research at Mead Johnson, director of pharmaceutical sciences at Adria Laboratories, and pharmaceutical manager at Analytical Biochemistry Laboratories. Most recently, he was a project officer at the National Cancer Institute.
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