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Psychiatric Genetics by Kenneth S. Kendler
Book DescriptionPsychiatric Genetics is a concise reference that presents the complexities of this dynamic field in a clearly written, easily accessible format, with numerous tables and illustrations. Ten expert contributors offer a fascinating view of psychiatric genetics in a text that is thorough and scholarly yet also succinct and accessible. The introduction summarizes the field's four distinct paradigms -- and their interrelationships -- that help us understand the role of genetic factors in the etiology of psychiatric disorders: basic genetic epidemiology, which demonstrates heritability; advanced genetic epidemiology, which explores the nature and mode of action of these genetic risk factors; gene finding, which enables us to infer the probability that a locus in the genomic region under investigation contributes to psychiatric disorder liability; and molecular genetics, which traces the biological mechanisms by which the DNA variant identified using gene finding methods contributes to the disorder itself. Psychiatric Genetics illustrates the importance of * Appreciating the complex field of psychiatric genetics -- Presents the major conceptual and statistical issues in psychiatric genetics, including many of the basic principles of both genetic epidemiology and gene finding, as well as a brief review of DNA itself.* Detailing the results for one disorder where substantial progress had been made in gene finding and molecular genetics -- Covers schizophrenia, because of the substantial progress made during the past few years.* Presenting results for a more typical and common set of psychiatric disorders where most of our information comes from basic and advanced genetic epidemiology and where we are just beginning to make advances using gene finding -- Discusses anxiety disorders, which illustrate these sets of issues.* Covering disorders where major advances have been made using basic and advanced genetic epidemiology -- Details substance use disorders, where the paradigm has shifted from sociological to genetic factors and where, in contrast to the genetics of more traditional psychiatric disorders, researchers must consider the inherent conditionality of drug abuse.* Investigating the role of genetics in personality disorders -- Focuses on the development of conduct and antisocial behavior and how to incorporate developmental processes into analyses of the role of genetics. Psychiatric Genetics draws students, educators, and practitioners alike into the exciting world of psychiatric genetics with a lively discussion of its broad trends and of the strengths and limitations of its methods to provide true insight into the etiology of psychiatric and substance use disorders.
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Book DetailsISBN: 9781585622283
(229mm x 152mm x 17mm)
Imprint: American Psychiatric Press Inc.
Publisher: American Psychiatric Association Publishing
Publish Date: 20-Apr-2005
Country of Publication: United States
Books By Author Kenneth S. Kendler
Philosophical Issues in Psychiatry III, Paperback (October 2014)
Psychiatry has been subject to major changes in the last 150 years. This book explores the forces that have shaped these changes and how they have impacted on the psychiatric profession in this time. The result is a dynamic discussion about the nature of psychiatric disorders, and a book that is compelling reading.
Philosophical Issues in Psychiatry II, Paperback (April 2012)
Psychiatry has long struggled with the nature of its diagnoses. This book brings together established experts in the wide range of disciplines that have an interest in psychiatric nosology. The contributors include philosophers, psychologists, psychiatrists, historians and representatives of the efforts of DSM-III, DSM-IV and DSM-V.
Dynamic Genome and Mental Health, Paperback (May 2011)» View all books by Kenneth S. Kendler
This volume contains the latest theories and evidence about the highly dynamic inter-relation between genes and environments as they influence the development, mental health and substance use of adolescents.
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Author Biography - Kenneth S. Kendler
Kenneth S. Kendler, M.D., Distinguished Professor, Departments of Psychiatry and Human Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, School of Medicine, Virginia Commonwealth University, Richmond, Virginia Lindon Eaves, Ph.D., D.Sc., Distinguished Professor, Departments of Human Genetics and Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, School of Medicine, Virginia Commonwealth University, Richmond, Virginia Together, Drs. Kendler and Eaves direct the Virginia Institute for Psychiatric and Behavioral Genetics.
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