Sample Size Calculations in Clinical Research
2nd Revised edition
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Sample Size Calculations in Clinical Research by Shein-Chung Chow
Book DescriptionFocusing on an integral part of pharmaceutical development, Sample Size Calculations in Clinical Research, Second Edition presents statistical procedures for performing sample size calculations during various phases of clinical research and development. It provides sample size formulas and procedures for testing equality, noninferiority/superiority, and equivalence. A comprehensive and unified presentation of statistical concepts and practical applications, this book highlights the interactions between clinicians and biostatisticians, includes a well-balanced summary of current and emerging clinical issues, and explores recently developed statistical methodologies for sample size calculation. Whenever possible, each chapter provides a brief history or background, regulatory requirements, statistical designs and methods for data analysis, real-world examples, future research developments, and related references. One of the few books to systematically summarize clinical research procedures, this edition contains new chapters that focus on three key areas of this field. Incorporating the material of this book in your work will help ensure the validity and, ultimately, the success of your clinical studies.
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Book DetailsISBN: 9781584889823
(234mm x 156mm x 29mm)
Imprint: Chapman & Hall/CRC
Publisher: Taylor & Francis Inc
Publish Date: 15-Aug-2007
Country of Publication: United States
Books By Author Shein-Chung Chow
Design and Analysis of Clinical Trials, Hardback (January 2014)
Clinical trials are conducted to allow safety and efficacy data to be collected for health interventions. These trials can only take place once satisfactory information has been gathered on the quality of the non-clinical safety.
Clinical Trial Methodology, Hardback (July 2010)» View all books by Shein-Chung Chow
Emphasizes the importance of statistical thinking in clinical research and presents the methodology as a key component of clinical research. From ethical issues and sample size considerations to adaptive design procedures and statistical analysis, the book first covers the methodology that spans various clinical trials.
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