Statistical Evaluation of Mutagenicity Test Data
Edited by David J. Kirkland
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Statistical Evaluation of Mutagenicity Test Data by David J. Kirkland
Book DescriptionThis rigorous and practical account of the interpretation of mutagenicity test data draws upon the expertise of toxicologists and statisticians. Chemicals, such as drugs, food additives and pesticides, all need careful screening to eliminate potentially mutagenic compounds. Although guidelines exist on the performance of these tests, advice on data evaluation is scarce; this volume provides the statistical background necessary for toxicologists to understand, design and interpret mutagenicity tests. In addition to the nine chapters dealing with the different tests employed, there is an introductory chapter on some of the statistical principles involved, a glossary of useful terms and an appendix providing vital information on the availability of computer software. A large team of contributors and editors working under the auspices of the United Kingdom Environmental Mutagen Society (UKEMS) have contributed a wealth of first-hand experience in compiling this immensely practical book of use to both research and industrial toxicologists.
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Book DetailsISBN: 9780521048149
(228mm x 152mm x 18mm)
Imprint: Cambridge University Press
Publisher: Cambridge University Press
Publish Date: 3-Jan-2008
Country of Publication: United Kingdom
Books By Author David J. Kirkland
Supplementary Mutagenicity Tests, Paperback (June 2011)
Originally published in 1993, this volume describes supplementary tests used to assess risks of in vitro mutagenicity when basic safety tests were inconclusive.
Basic Mutagenicity Tests, Paperback (September 2005)
A summary of the essential texts that must be performed on all new compounds before they can be registered for use in the UK.
Statistical Evaluation of Mutagenicity Test Data, Hardback (December 1989)» View all books by David J. Kirkland
This rigorous and practical account of the interpretation of mutagenicity test data draws upon the expertise of toxicologists and statisticians.
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