A Powerful Tool for Toxicity Assessment
By (author) Saura C. Sahu
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Toxicogenomics by Saura C. Sahu
Book DescriptionToxicogenomics is the integration of genomics to toxicology. This technology is a powerful tool for collecting information from a large number of biological samples simultaneously and thus it is very useful for large-scale screening of potential toxicants. Toxicogenomics: A Powerful Tool For Toxicity Assessment provides up-to-date state-of-the-art information presented by the recognized experts, and is therefore an authoritative source of current knowledge in this field of research. The potential link between toxicology, genetics and human diseases makes this book very useful to investigators in many and varied disciplines of science and toxicology. Topics covered include: * mechanistic toxicogenomics * analysis and interpretation of toxicogenomic data * principles of data mining in toxicogenomics * design issues in toxicogenomics studies * sources of variability in toxicogenomic assays Escherichia coli stress response as a tool for detection of toxicity * toxicogenomics as a tool to assess immunotoxicity * toxicogenomics and ecogenomics for studying endocrine disruption and basic biology * use of toxicogenomics as an early predictive tool for hepatotoxicity * nutrigenomics: the application of genomic signatures in nutrition-related research * application of toxicogenomics in drug discovery * potential uses of toxicogenomic biomarkers in occupational health and risk assessment * usefulness of toxicogenomics in the regulatory environment * perspectives on toxicogenomics at the US Environmental Protection Agency Toxicogenomics: A Powerful Tool For Toxicity Assessment is an essential resource for research scientists currently engaged in toxicogenomics, and will also be of interest to researchers working in toxicology, genetics, medicine, pharmacology, and food sciences, and to regulators and risk assessors of drug, food, environmental and agricultural products.
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Book DetailsISBN: 9780470518236
(253mm x 176mm x 28mm)
Publisher: John Wiley and Sons Ltd
Publish Date: 17-Oct-2008
Country of Publication: United States
Books By Author Saura C. Sahu
Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology, Hardback (May 2014)
The Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology provides an insight into the current trends and future directions of research in these rapidly developing scientific fields.
MicroRNAs in Toxicology and Medicine, Hardback (October 2013)
Providing insight into the trends and future directions of research in this rapidly developing new field, this book offers a comprehensive and authoritative compilation of developments in the role of Micrornas in disease and their use in toxicology.
Toxicology and Epigenetics, Hardback (September 2012)» View all books by Saura C. Sahu
This book describes cutting-edge molecular technologies to unravel epigenetic changes, the use of in vivo and in vitro models, as well as the potential use of toxicological epigenetics in regulatory environments.
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