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Organophosphorus Chemistry: A Practical Approach in Chemistry provides a practical introduction to the field by mixing a brief review of the subject area with key experimental details and sample procedures. Phosphorus is an element that has been central to the development of our modern way of life. Its chemistry plays a key role in the development of such important areas as pharmaceuticals, agrochemicals, modern materials and molecular biology. Much of this work requires a sound understanding of the organic chemistry of phosphorus and this volume is designed to instruct the reader in the essential methodology used. Topics covered include phosphines, applications of phosphorus (III) and (V) compounds as reagents in synthesis, the chemistry of phosphorus ylides, applications of the Wittig reaction in the synthesis of heterocyclic and carbocyclic compounds, preparation of Iminophosphoranes and their synthetic applications in the aza-Wittig reaction, phospho-transfer processes leading to [P-C] bond formation, low valent phosphorus compounds and phosphorus methods in oligonucleotide chemistry. It is intended not only for the specialist in organophosphorus chemistry, but also for the organic chemist with little experience in the field who wishes to add phophorus-based techniques to his or her ensemble of synthetic methods.

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Book Details

ISBN: 9780198502623
ISBN-10: 0198502621
Format: Hardback
(242mm x 162mm x 20mm)
Pages: 288
Imprint: Oxford University Press
Publisher: Oxford University Press
Publish Date: 22-Jul-2004
Country of Publication: United Kingdom


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Author Biography - Patrick J. Murphy

Dr Patrick J Murphy is currently a senior lecturer in Organic Chemistry at the University of Wales, Bangor. His research interests include organo-phosphorus chemistry, guanidine chemistry and natural product synthesis

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