Noeline Latt is an Addiction Medicine Specialist with a background in clinical pharmacology. She is a Senior Staff Specialist in Addiction Medicine at Royal North Shore Hospital in Sydney, Clinical Lecturer at the University of Sydney, Consultant to the NSW Drug and Alcohol Specialist Advisory Service and a Foundation Fellow of the Chapter of Addiction Medicine, Royal Australasian College of Physicians. She has more than 15 years' experience in clinical treatment and teaching of alcohol and substance use disorders. Her research has focussed on treatment of alcohol dependence, Hepatitis C in pregnant injecting drug users and substance induced psychosis. Kate Conigrave is an Addiction Medicine Specialist and a Public Health Physician. As well as her clinical practice as a Staff Specialist in Addiction Medicine at Royal Prince Alfred Hospital she has extensive research experience in alcohol and drug use disorders. A/Prof Conigrave has conjoint appointments at the Faculty of Medicine, University of Sydney, The National Drug and Alcohol Research Centre, University of New South Wales, and Menzies School of Population Health Research, Darwin. Her research has a focus on detection and early intervention for alcohol problems, and how to better implement evidence-based practice into the clinical routine. In recent years she has also worked with Aboriginal and Torres Strait Islander communities on addressing substance use disorders. A/Prof Conigrave has acted as short term consultant to the World Health Organization on brief intervention. She is on the Editorial advisory board for Alcohol and Alcoholism. John Saunders is the Professor of Alcohol and Drug Studies at the University of Queensland and Director of the Alcohol and Drug Services of The Prince Charles Hospital and Royal Brisbane Hospital Health Service Districts. After qualifying in medicine from the University of Cambridge he specialised in acute general medicine, gastroenterology and drug and alcohol medicine. He has been a practising clinician, researcher, teacher and manager in drug and alcohol services for more than 25 years. He has worked closely with the World Health Organization for many years, being Scientific Director of WHO's collaborative studies on brief intervention, and responsible for devising the AUDIT questionnaire. He has published two books and more than 250 scientific papers. Jane Marshall is a Consultant Psychiatrist in Alcohol Studies at the South London and Maudsley NHS Foundation Trust and Senior Lecturer in the Addictions at the National Addiction Centre, Institute of Psychiatry, Kings College London. She trained in Psychiatry at St Patrick's Hospital, Dublin and St Bartholomew's and the Maudsley Hospitals in London. Her clinical work is currently focused on a specialist out-patient and in-patient alcohol service, also a service for addicted healthcare professionals. Education and training commitments include being lead clinician for an MSc programme in the Clinical and Public Health Aspects of Addiction, based at the Institute of Psychiatry. Research interests include the evaluation of treatment for alcohol problems in specialist and generalist settings and, in particular, treatment for addicted healthcare professionals. David Nutt is currently Professor of Psychopharmacology and Head of the Department of Community Based Medicine at the University of Bristol. He received his undergraduate training in medicine at Cambridge and Guy's Hospital, and continued training in neurology to MRCP. After completing his psychiatric training in Oxford, he continued there as a lecturer and then later as a Wellcome Senior Fellow in psychiatry. He then spent two years as Chief of the Section of Clinical Science in the National Institute of Alcohol Abuse and Alcoholism in NIH, Bethesda, USA. On returning to England in 1988 he set up the Psychopharmacology Unit in Bristol, an interdisciplinary research grouping spanning the departments of Psychiatry and Pharmacology. Their main research interests are in the brain mechanisms underlying anxiety, depression and addiction and the mode of action of therapeutic drugs.