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The colony-stimulating factors (CSFs) are the major regulators in the body of the production and activity of two types of white blood cells - granulocytes and macrophages. This book provides a detailed account of the discovery of the CSFs, their structure, molecular biology and cellular receptors, the biology of the CSFs in vivo and in vitro and their present and future clinical applications. Written by two of the pioneers in the discovery of CSFs, it is a clear and well-illustrated survey of the history, knowledge and future directions of this exciting field of investigation, and serves also as a guide to the more general areas of growth factor and cytokine research. It will prove an invaluable review for cell biologists interested in how growth factors act on the body, as well as for clinicians applying the fruits of modern biotechnology to improved patient care.

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Book Details

ISBN: 9780521034814
ISBN-10: 0521034817
Format: Paperback
(228mm x 152mm x 20mm)
Pages: 356
Imprint: Cambridge University Press
Publisher: Cambridge University Press
Publish Date: 14-Dec-2006
Country of Publication: United Kingdom

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Books By Author Donald Metcalf

Hemopoietic Colony-stimulating Factors by Donald Metcalf

The Hemopoietic Colony-stimulating Factors

Hardback, February 1995