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MicroRNAs (miRNAs) are RNA molecules, conserved by evolution, that regulate gene expressions and their discovery has revolutionised both basic biomedical research and drug discovery. Expression levels of miRNAs have been found to vary between tissues and with developmental stages and hence evaluation of the global expression of miRNAs potentially provides opportunities to identify regulatory points for many different biological processes. This wide-ranging reference work, written by leading experts from both academia and industry, will be an invaluable resource for all those wishing to use miRNA techniques in their own research, from graduate students, post-docs and researchers in academia to those working in R&D in biotechnology and pharmaceutical companies who need to understand this emerging technology. From the discovery of miRNAs and their functions to their detection and role in disease biology, this volume uniquely integrates the basic science with industry application towards drug validation, diagnostic and therapeutic development.

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Book Details

ISBN: 9780521865982
ISBN-10: 0521865980
Format: Hardback
(253mm x 177mm x 32mm)
Pages: 580
Imprint: Cambridge University Press
Publisher: Cambridge University Press
Publish Date: 20-Dec-2007
Country of Publication: United Kingdom

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Author Biography - Krishnarao Appasani

Krishnarao Appasani is the Founder and Chief Executive Officer of Gene Expression Systems, a gene discovery company, focusing on functional genomics in cancer research. He is the Editor of RNA Interference: From Basic Science to Drug Development (2005).

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