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An increasing number of pharmaceuticals in human and veterinary medicine are being developed using advanced genetic and other methods that focus on modification of somatic and embryonic cells. These methods, in the setting of drug manufacture, call for new processes that go beyond the traditional unit processes of chemical and biological production, such as batch submerged culture. This book is the first to describe in detail these advanced biological processes and show how they are applied to the production of biopharmaceuticals, from product generation and purification to fill-finish operations. The work explains how technologies developed in the last decade function similarly to unit operations for producing advanced biopharmaceuticals, such as hormones, cytokines, therapeutic enzymes, modified proteins, and transgenic products - to name a few. From large-scale animal cell bioreactors to patient-customized products, this volume describes the effects of new technologies on biopharmaceutical processes and guides users on how to apply new technologies in process development.

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Book Details

ISBN: 9780813805177
ISBN-10: 0813805171
Format: Hardback
(235mm x 157mm x 20mm)
Pages: 284
Imprint: Iowa State University Press
Publisher: Iowa State University Press
Publish Date: 9-Jan-2007
Country of Publication: United States

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Author Biography - Roshni Dutton

Roshni Dutton Ph.D., Associate Professor, Dept. of Chemical Engineering, Ryerson University, Toronto, Canada and President, Bioprocess Assist (BPA) Ltd., Aberfoyle, Ontario, Canada Jeno Scharer Ph.D. Professor Emeritus, Department of Chemical Engineering, University of Waterloo, Canada