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Description - Transfusion-Free Medicine and Surgery by Nicolas Jabbour

SUBJECT: The field of transfusion-free medicine and surgery is a new discipline that has evolved over the last seven to eight years. The Jehovah's Witness community initially drove this arena based on their religious belief, which prohibits any blood or blood product transfusion. However, due to the increasing concern about the overall safety of blood and blood products and the shortage of blood, there are an increasing number of patients who are interested in alternatives to blood transfusion. It is also important to note that by law, physicians are obliged to tell their patients about the risk of blood transfusion and the available alternatives such as pre-donation of blood. Soon these regulations will include some, if not most, of the techniques and ideas that will be included in this book. Transfusion-free medicine is accomplished through pharmaceutical therapy, blood conservation and meticulous surgical techniques to minimize blood loss. NEED: The Transfusion-Free Medicine and Surgery Program at USC started over five years ago. It was the second program established in the Los Angeles area. Currently, there are over 10 such programs in the same geographic area. It is one of the most renowned programs in the world due to its accomplishments and mainly the performance of 14 bloodless or transfusion-free liver transplantations, ten of which came from live donors. No other program in the world has performed live donor liver transplantations in patients. Although the book seems to cover a very small niche within a sub-specialty, its use will be widespread and it will include all specialties in medicine, given that most transfusion-free programs cover almost all available specialties in the hospital. For example at the program at USC, over 125 major surgical procedures have been performed in Jehovah's Witness patients over the last four years. These surgeries include liver transplantation, major liver or pancreatic surgery, major colon surgery, neurosurgery, orthopedic surgery, lung and heart surgery and major vascular surgery. All surgical disciplines, along with internal medicine, ICU care and anaesthesia would therefore be interested in this topic. COMPETITION: Currently, there are no concise books or manuals for either physicians or patients that summarize the issues related to blood products, blood transfusion and transfusion-free medicine and surgery. There is one medical journal, Transfusion Alternatives in Transfusion Medicine, which covers topics related to this field and is published through the Network for Advancement of Transfusion Alternatives. FORMAT: The book will be divided into nine chapters. It will begin with a discussion of the origin of the field and the right of patients to refuse blood transfusion. This will be followed by a discussion of the issues related to blood transfusion, including the amount of blood used worldwide, the risk of blood transfusion, the potential shortage of blood and the cost of blood and blood products. The next chapters will discuss the physiology of anaemia and the safe threshold for blood transfusion, preoperative management and preparation, intraoperative strategy and postoperative management. The book will conclude with a chapter on the status of artificial blood products, their limitations, clinical use and their approval by the FDA. CONTENT AND ORGANISATION: See contents list below. MARKETING: . Currently, there are three national and international associations involved in transfusion-free medicine and surgery. These are: (a) NABM - National Association of Bloodless Medicine; (b) NATA - Network for Advancement of Transfusion Alternatives; (c) SABM - Society for Advancement of Blood Management. (Dr Jabbour is a founding member and sits on the board of directors). These societies meet at least once a year with usually over 300 participants. The societies are involved in promoting and developing the field of transfusion-free medicine and surgery across the nation and worldwide. We can also reach our haematology amd transfusion readers with our large presence in this area. FEATURES:Discusses controversial issues associated with transfusion-free medicine and surgery. Includes latest research in the field, including the latest techniques in bloodless medicine. MCQ's at the end of the book to serve as an exam for physician certification and act as a CME tool.SPONSORSHIP: Novo-Nordisk has committed to sponsorsng the project by providing an outright grant of $51,000. They will take 200 copies in the USA, but the final print run and price will be set by us. The company manufactures factor 7-A which allows transfusion-free surgery to take place by enhancing the clotting system. They do, however, not have exclusive rights to the book and there are other companies we can approach. First, Amgen which manufactures Epogen, one of its major selling drugs with over one billion in annual sales. The drug increases red blood cell mass prior to or after surgery and is routinely used in chronic renal patients and patients with tumours. Second, Ortho-Bio Tech which manufactures Procrit, a drug similar to Epogen. It is used for the same indications. There are also other companies that are currently involved in developing an artificial blood component for oxygen transport to avoid or minimize blood transfusion. SUPPORT: Dr Nicolas Jabbour is the Medical Director of the USC Transfusion-free Medicine and Surgery Program and Assistant Professor of Surgery at the Keck School of Medicine of USC. Since the program's inception in 1997, 2000 patients have been treated and in 1999 his transplantation team performed the first two successful transfusion-free live donor liver transplantations in the USA. SUMMARY: An essential guide to the new field of transfusion-free medicine and surgery written by one of the leading experts in the field.

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Book Details

ISBN: 9781405121590
ISBN-10: 1405121599
Format: Hardback
(241mm x 159mm x mm)
Pages: 312
Imprint: Wiley-Blackwell (an imprint of John Wiley & Sons Ltd)
Publisher: John Wiley and Sons Ltd
Publish Date: 19-Sep-2005
Country of Publication: United Kingdom

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Author Biography - Nicolas Jabbour

Professor Nicolas Jabbour, Assistant Professor of Surgery, Associate Director Liver Transplantation Surgery, Keck School of Medicine, University of Southern California, USA

Books By Nicolas Jabbour

Transfusion Free Medicine and Surgery by Nicolas Jabbour
Hardback, September 2014