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Description - Pediatric Solid Organ Transplantation by Richard N. Fine

SUBJECT:Children with end-stage organ failure generally have different underlying diseases, immune responses, medical and surgical complications of organ transplantation and different treatment end-points than adults. Therefore, those who provide transplant care for children should be aware of these differences and be experienced in dealing with them. Paediatric solid organ transplantation has experienced exciting and substantial advances in the past decade as a result of continued inprovement in clinical outcomes. This has been due to improvements in surgical techniques, donor selection, knowledge of paediatric pharmacokinetics, pharmacodynamics and the development of specialised paediatric transplant teams. Children, however, do experience more complications. Rejection occurs more frequently than in adult patients, infections are more common and donors are harder to find. New anti-rejection drugs and new drug combinations more effectively control rejection and prevent or treat serious infection with fewer side effects. Innovative surgical techniques, such as transplanting lobes of lungs, are helping alleviate the clinical donor shortage for younger patients. NEED:There is a need for a new, comprehensive text on all aspects of paediatric solid organ transplantation. We published Paediatric Solid Organ Transplantation through our Copenhagen office in 2000. However, this book was put together by the council of the International Paediatric Transplant Association in time for their bi-annual congress and the original editors felt that, owing to time restrictions, the final book was not a comprehensive resource on paediatric transplantation. The new book will use some of the material from the aboce book, but be completely revised and updated throughout. COMPETITION:There is no single reference source that covers the whole field of paediatirc organ transplantation. There are, however, multi-authored books directed at specific types of organ transplantation such as renal, heart and stem cell. FORMAT:The book will be divided into seven sections. The first two sections will provide information about the immune system, rejection and tolerance, immunosuppressives and infections - issues common to all organs. Each subsequent section will be organ specific and structured in a common format designed to cover transplantation while maintaining the unique needs of the organ speciality. For example, every section will look at the issues relating to donor and recipient characteristics and evaluation. There will then be a discussion of pre-transplantation management, before surgical techniques and management are covered. Subsequent chapters will deal with post-transplant management, outcome and risk factors. The final chapter in each section will discuss specific issues such as rehabilitation and growth, psychologic and psychosocial implications together with complications of infections and rejection. Renal, liver, cardiac, small bowel and lung transplantation will all be covered in detail.The main editor, Professor Fine, has recruited two new editors for this book. Both are highly respected clinicians in paediatric transplantation. The editorial team will assemble an international team of over 60 contributors to cover the entire field of paediatric transplantation. CONTENTS AND ORGANISATION:See contents list below. FEATURES: Comprehensive reference source covering all aspects of paediatric solid organ transplantation in one volume. Sections cover basic science, in addition to organ-specific transplantations. Standard template for each chapter to navigate the reader through key issues for each type of organ transplant.MARKETING:We have a major presence in transplantation through our journal publishing program. As the publishers of Paediatric Transplantation we have direct access to all members of the International Pediatric Transplant Association (over 550). In addition, we aim to publish the book in time for their bi-annual meeting whch takes place in Innsbruck in June 2005. We are discussing inclusion of the book with the registration fee to ensure each member automatically recieves a copy. PAST HISTORY:The first edition was published through our Copenhagen office in 2000 and we are unable to obtain accurate sales data, but believe sales have been in the region of 200-300 copies. At this time our presence in the field was not so strong and the speciality of paediatric transplantation was in its infancy. SUMMARY:A comprehensive text on paediatric transplantation that will be used by all those working in transplant centres and also provide a cohesive approach to the teaching of paediatric transplantation in various subspecialities. SUPPORT:Professor Richard Fine is the current editor of our journal Pediatric Transplantation, which is the official publication of the International Paediatric Transplant Association, and the Secretary/Treasurer of the American Society of Transplantation. Dr Steven Webber is an international expert in the field of paediatric cardiac transplantation and Dr William Harman has just stepped down from his role as President of the American Society of Transplantation.

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Book Details

ISBN: 9781405124072
ISBN-10: 1405124075
Format: Hardback
(285mm x 224mm x 32mm)
Pages: 488
Imprint: Wiley-Blackwell (an imprint of John Wiley & Sons Ltd)
Publisher: John Wiley and Sons Ltd
Publish Date: 24-Jan-2007
Country of Publication: United Kingdom

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Author Biography - Richard N. Fine

Professor Richard Fine, Professor and Chairman, Department of Paediatrics, State University of New York, USA Dr Steve Webber, Division of Cardiology, Children's Hospital of Pittsburgh, USA Dr William Harman, Associate Professor of Paediatrics, Harvard Medical School, Boston, USA