Description - Catalysis in Asymmetric Synthesis by Vittorio Caprio
Asymmetric synthesis has become a major aspect of modern organic chemistry. The stereochemical properties of an organic compound are often essential to its bioactivity, and the need for stereochemically pure pharmaceutical products is a key example of the importance of stereochemical control in organic synthesis. However, achieving high levels of stereoselectivity in the synthesis of complex natural products represents a considerable intellectual and practical challenge for chemists. Written from a synthetic organic chemistry perspective, this text provides a practical overview of the field, illustrating a wide range of transformations that can be achieved. The book captures the latest advances in asymmetric catalysis with emphasis placed on non-enzymatic methods.
Topics covered include:* Reduction of alkenes, ketones and imines* Nucleophilic addition to carbonyl compounds* Catalytic carbon-carbon bond forming reactions* Catalytic reactions involving metal carbenoids* Conjugate addition reactions Catalysis in Asymmetric Synthesis bridges the gap between undergraduate and advanced level textbooks and provides a convenient point of entry to the primary literature for the experienced synthetic organic chemist.
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(227mm x 154mm x 22mm)
Wiley-Blackwell (an imprint of John Wiley & Sons Ltd)
Publisher: John Wiley and Sons Ltd
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Author Biography - Vittorio Caprio
Dr Vittorio Caprio is Lecturer in Organic and Medicinal Chemistry in the Department of Chemistry, University of Auckland, Auckland, New Zealand