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Description - Hepatic Fibrosis: Pathogenesis, Diagnosis and Emerging Therapies by Scott Friedman

Hepatic fibrosis is the final common pathway for a multitude of liver injuries. Viral-, immune-, or toxin-mediated liver injuries all result in expansion of the extracellular matrix with distortion of hepatic architecture and development of cirrhosis. Originally thought of as a one-way street, hepatic fibrosis now is recognized as a dynamic process with the potential for significant resolution. Authors in this issue address the genetic determinants of fibrosis, oxidant stress, cellular contractility and vasoregulation, as well as relationships between stellate cell activation, progenitor cells and hepatic regeneration. Current and future antifibrotic therapies are also discussed.

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Book Details

ISBN: 9781416063155
ISBN-10: 1416063153
Format: Hardback
Pages: 240
Imprint: Saunders
Publisher: Elsevier - Health Sciences Division
Publish Date: 1-Nov-2008
Country of Publication: United States

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