Description - Enzyme Systems That Metabolise Drugs and Other Xenobiotics by Costas Ioannides
This definitive reference work describes in detail the enzyme systems that participate in the metabolism of xenobiotics, particularly medicinal drugs. Each chapter focuses on a specific enzyme system, emphasising its role in the activation and detoxication of chemicals. Aspects discussed critically include:
* enzyme function in the metabolism and bioactivation of xenobiotics
* substrate specificity
* tissue distribution
* species distribution (to include laboratory animals and humans)
* hormonal regulation
* sex differences
* modulation by prior exposure to other chemicals
* age-dependent expression
* pharmacogenetics and modulation by disease.
Enzyme Systems that Metabolise Drugs and Other Xenobiotics will be essential reading for industrial research scientists working in the fine chemicals and pharmaceutical industries, especially those concerned with the safety evaluation of chemicals, and investigating their metabolism, pharmacokinetic characteristics and toxicological properties. The nature and scope of the book will also make it attractive to the research toxicologist and to postgraduate students studying toxicology, as well as to clinicians and pharmacists.
Buy Enzyme Systems That Metabolise Drugs and Other Xenobiotics by Costas Ioannides from Australia's Online Independent Bookstore, Boomerang Books.
(237mm x 160mm x 37mm)
John Wiley & Sons Ltd
Publisher: John Wiley and Sons Ltd
Country of Publication:
Book Reviews - Enzyme Systems That Metabolise Drugs and Other Xenobiotics by Costas Ioannides
» Have you read this book? We'd like to know what you think about it - write a review about Enzyme Systems That Metabolise Drugs and Other Xenobiotics book by Costas Ioannides and you'll earn 50c in Boomerang Bucks loyalty dollars (you must be a Boomerang Books Account Holder - it's free to sign up and there are great benefits!)