Call Boomerang Books 1300 36 33 32

Description - Kinetic Analysis of Macromolecules by Kenneth Johnson

Modern enzymology can no longer rely upon indirect inferences derived by steady state kinetic analysis because these are often misleading. Rather, in the era of 'New Enzymology', reactions at the active sites of enzyme are monitored by direct measurement of individual steps in the sequence to establish the pathway of reactions occurring. These quantitative methods can be directly related to high resolution structural information and define the underlying kinetic and thermodynamic basis for catalysis. The goal of a comprehensive kinetic analysis is to identify each step in the reaction pathway, define the rate and equilibrium constants for each step, identify all conformational and chemical intermediates, identify the rate-limiting steps, and ultimately establish the basis for enzymatic specificity and efficiency. This volume contains chapters contributed by the leading experts in the application of modern kinetic methods to complex problems in the study of catalysis by both proteins and RNA catalysts.
Each chapter focuses on a unique system and the novel methods used to obtain definitive data that can be directly applied to structural information, giving the much-needed practical details that are often omitted in the general literature. Readers will benefit greatly from the richness of each chapter in describing what is most important in solving the most difficult problems in modern enzymology.

Buy Kinetic Analysis of Macromolecules by Kenneth Johnson from Australia's Online Independent Bookstore, Boomerang Books.

Book Details

ISBN: 9780198524939
ISBN-10: 0198524935
Format: Hardback
(254mm x 195mm x 21mm)
Pages: 276
Imprint: Oxford University Press
Publisher: Oxford University Press
Publish Date: 1-Oct-2003
Country of Publication: United Kingdom

Book Reviews - Kinetic Analysis of Macromolecules by Kenneth Johnson

» Have you read this book? We'd like to know what you think about it - write a review about Kinetic Analysis of Macromolecules book by Kenneth Johnson and you'll earn 50c in Boomerang Bucks loyalty dollars (you must be a Boomerang Books Account Holder - it's free to sign up and there are great benefits!)

Author Biography - Kenneth Johnson

Kenneth A. Johnson Roger Williams Centennial Professor of Biochemistry Institute for Cell & Molecular Biology, University of Texas, A4800 MBB 3.122, Austin, TX 78735 512-471-0434 512-471-0435 Roger Williams Centennial Professor of Biochemistry The University of Texas at Austin Recipient of Pfizer Award in Enzyme Chemistry, 1989 Founder and President of KinTek Corporation, manufacturer of stopped-flow and quench-flow instruments for fast reaction kinetics. Editorial Board Member, Journal of Biological Chemistry