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Description - The Picornaviruses by Ellie Ehrenfeld

A springboard for developing new approaches to understanding, preventing, and treating picornaviral diseases. * Examines the most current breakthroughs as well as the challenges that lie ahead in picornavirus research; encapsulates current knowledge of the molecular biology, evolution, and pathogenesis of this large family of viruses; and, examines the diseases that these viruses cause and the latest vaccines and antiviral drugs to prevent and control those diseases. * Explores the structural and mechanistic bases of picornavirus replication, highlighting new insights about the host cell interactions needed for virus growth; and, illustrates how the regular occurrence of mutations, typical of viruses with RNA as genetic material, generates the quasispecies dynamics that underlie viral fitness. * Focuses on picornaviruses that cause disease, examining pathogenicity and innate and acquired immune responses against infection as well as the latest vaccine and antiviral drug strategies. This title is published by the American Society of Microbiology Press and distributed by Taylor and Francis in rest of world territories.

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Book Details

ISBN: 9781555816032
ISBN-10: 1555816037
Format: Hardback
(287mm x 224mm x 29mm)
Pages: 536
Imprint: American Society for Microbiology
Publisher: American Society for Microbiology
Publish Date: 15-Sep-2010
Country of Publication: United States

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Author Biography - Ellie Ehrenfeld

Ellie Ehrenfeld, National Institute of Allergy and Infectious Diseases, National Institutes of Health Esteban Domingo, Centro de Biologia Molecular Severo Ochoa (CSIC-UAM), Universidad Autonoma de Madrid Raymond P. Roos, Department of Neurology, University of Chicago