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Description - Regenerative Medicine Applications in Organ Transplantation by Giuseppe Orlando

Regenerative Medicine Applications in Organ Transplantation illustrates exactly how these two fields are coming together and can benefit one another. It discusses technologies being developed, methods being implemented, and which of these are the most promising. The text encompasses tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, all from a transplant perspective. Organ systems considered include liver, renal, intestinal, pancreatic, and more. Leaders from both fields have contributed chapters, clearly illustrating that regenerative medicine and solid organ transplantation speak the same language and that both aim for similar medical outcomes. The overall theme of the book is to provide insight into the synergy between organ transplantation and regenerative medicine. Recent groundbreaking achievements in regenerative medicine have received unprecedented coverage by the media, fueling interest and enthusiasm in transplant clinicians and researchers. Regenerative medicine is changing the premise of solid organ transplantation, requiring transplantation investigators to become familiar with regenerative medicine investigations that can be extremely relevant to their work. Similarly, regenerative medicine investigators need to be aware of the needs of the transplant field to bring these two fields together for greater results.

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Book Details

ISBN: 9780123985231
ISBN-10: 0123985234
Format: Hardback
(276mm x 216mm x mm)
Pages: 1050
Imprint: Academic Press Inc
Publisher: Elsevier Science Publishing Co Inc
Publish Date: 5-Nov-2013
Country of Publication: United States

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Author Biography - Giuseppe Orlando

Transplant surgeon scientist, specializing in kidney and pancreas transplantation, as well as in abdominal organ bioengineering and regeneration. My main achievements have been in the field of steroid-free immunosuppression (IS), IS minimization and clinical tolerance after liver transplantation, as well as in the development of platforms for renal, small bowel and endocrine pancreas bioengineering and regeneration research. The main goal of my investigations is to bio-engineer and implant in humans renal organoids, insulin-producing cells and segments of small bowel. The ability to produce kidneys, insulin-producing cells and small bowel from patient's own cells will revolutionize transplant medicine. The main goal of my scientific production is to orchestrate the transition of organ transplantation towards a regenerative medicine-focused type of research. I originally hail from Rome, Italy, where I grew up, matriculated, attended medical school, and received training in general and transplant surgery. I also participated in fellowships in Paris (Liver Unit, Paul Brousse Hospital, Dir: Henri Bismuth, 6 months) and Brussels (General and Transplant Surgery, Catholic University of Leuven, Dir: Jan Lerut, Jean Bernard Otte, Jean De Ville De Goyet, 31 months). 2006-2008, I was a practicing transplant surgeon at the University of L'Aquila, Italy. 2008-2011, I received and implemented the distinguished Marie Curie International Outgoing Fellowship, for which I spent 2 years at the Wake Forest Institute of Regenerative Medicine (Winston Salem, USA) and 1 year at the Transplant Research Immunology Group (Oxford, UK), specializing in organ bioengineering and regeneration and transplant immunology. I have authored more than 135 research papers, review articles, and book chapters. I have just published - as editor in chief - a book on organ transplantation and regenerative medicine which is destined to set a new standard in transplant and regenerative medicine literature and to become a referral work for the future generations of specialists of both fields. I am a member of numerous transplant societies and am on the board and act as a regular reviewer for a number of relevant journals.