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Description - Sample Size Calculations in Clinical Research, Third Edition by Shein-Chung Chow

Praise for the Second Edition:

"... this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study." -Biometrics

"This impressive book contains formulae for computing sample size in a wide range of settings. One-sample studies and two-sample comparisons for quantitative, binary, and time-to-event outcomes are covered comprehensively, with separate sample size formulae for testing equality, non-inferiority, and equivalence. Many less familiar topics are also covered ..." - Journal of the Royal Statistical Society

Sample Size Calculations in Clinical Research, Third Edition presents statistical procedures for performing sample size calculations during various phases of clinical research and development. A comprehensive and unified presentation of statistical concepts and practical applications, this book includes a well-balanced summary of current and emerging clinical issues, regulatory requirements, and recently developed statistical methodologies for sample size calculation.

Features:

  • Compares the relative merits and disadvantages of statistical methods for sample size calculations
  • Explains how the formulae and procedures for sample size calculations can be used in a variety of clinical research and development stages
  • Presents real-world examples from several therapeutic areas, including cardiovascular medicine, the central nervous system, anti-infective medicine, oncology, and women's health
  • Provides sample size calculations for dose response studies, microarray studies, and Bayesian approaches

This new edition is updated throughout, includes many new sections, and five new chapters on emerging topics: two stage seamless adaptive designs, cluster randomized trial design, zero-inflated Poisson distribution, clinical trials with extremely low incidence rates, and clinical trial simulation.

Buy Sample Size Calculations in Clinical Research, Third Edition by Shein-Chung Chow from Australia's Online Independent Bookstore, Boomerang Books.

Book Details

ISBN: 9781138740983
ISBN-10: 1138740985
Format: Hardback
(254mm x 178mm x mm)
Pages: 510
Imprint: CRC Press
Publisher: Taylor & Francis Ltd
Publish Date: 30-Aug-2017
Country of Publication: United Kingdom

Book Reviews - Sample Size Calculations in Clinical Research, Third Edition by Shein-Chung Chow

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