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Description - T Cell Subsets by Frederick W. Alt

This first thematic issue, of the Advances in Immunology series, highlights the remarkable new insights into the mechanisms that govern development and function of T cell lineages. Recent developments in the understanding of the genetic and epigenetic mechanisms that regulate development of the two major T cell lineages will have a fundamental impact on a number of research fields -immunology, cell biology, hematology and stem cell research. All of these groups have a vested interest in comprehending issues such as stem cell self renewal, progenitor plasticity, lineage commitment and cellular identity. Immunologists have a special interest in the mechanisms that allow selection of a T cell repertoire whose members integrate genetic information for T cell receptor, co-receptor and specialized immunologic function, since this process lies at the core of adaptive immunity. T Cell Subsets is a timely and invaluable review for immunologists, cell biologists hematologists and stem cell researchers

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Book Details

ISBN: 9780120224838
ISBN-10: 0120224836
Format: Hardback
(229mm x 152mm x mm)
Pages: 304
Imprint: Academic Press Inc
Publisher: Elsevier Science Publishing Co Inc
Publish Date: 20-May-2004
Country of Publication: United States

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