Description - X-Ray Crystallography of Biomacromolecules by Albrecht Messerschmidt
Written by one of the most significant contributors to the progress of protein crystallography, this practical guide contains case studies, a troubleshooting section and pointers on data interpretation. It covers the theory, practice and latest achievements in x-ray crystallography, such that any researcher in structural biology will benefit from this extremely clearly written book. Part A covers the theoretical basis and such experimental techniques as principles of x-ray diffraction, solutions for the phase problem and time-resolved x-ray crystallography. Part B includes case studies for different kinds of x-ray crystal structure determination, such as the MIRAS and MAD techniques, molecular replacement, and the difference Fourier technique.
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(241mm x 174mm x 21mm)
Wiley-VCH Verlag GmbH
Publisher: Wiley-VCH Verlag GmbH
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Author Biography - Albrecht Messerschmidt
Professor Dr. Albrecht Messerschmidt is group leader at the Max Planck Institute for Biochemistry, Marinsried, Germany.
His main reserach interest is in the determination of X-ray structures of metalloproteins and -enzymes, PLP-dependent enzymes, CoA-transferases and other proteins. His group is part of the department of X-ray structure determination of proteins headed by nobel laureate Robert Huber.